Men's and Women's Cross Country/Track, Baseball, Softball, Women's Volleyball, Football, Esports, and Cheerleading. Louisburg competes in the NJCAA in varying divisions depending on team.
== Notable people ==
Archibald Hunter Arrington ‘18 – politician, County Commissioner in 1868
Fanny Yarborough Bickett, First Lady of North Carolina and first female president of the North Carolina Railroad
Ellis Credle ‘22 – author, Down Down the Mountain
Joseph J. Davis ’48 – politician and lawyer – US House of Representatives, 1875
=== Sports ===
Bill Moran '71 – baseball player
Mike Dement '74 – college basketball coach
Ron Musselman '75 – baseball player
Mark Funderburk '76 – baseball player
Kelly Heath '77 – baseball player
Brian Holton '78 – baseball player
Otis Nixon '79 – baseball player
Greg Briley '85 – baseball player
Theodore "Blue" Edwards '86 – basketball player
Russell Scott Riggs '91 – racecar driver
Chad Fonville '92 – baseball player
Travis Cherry '96 – musician
Josh Rupe '02 – baseball player
Ian Drew …
