and his brother Charles Horace Mayo was a professor of surgery at the University of Minnesota Medical School. In its early years, the Mayo Clinic was operated as a for-profit hospital and could not affiliate with the university.
This led to the creation of the Mayo Foundation for Medical Education and Research (MFMER) in 1915. MFMER was established as a department of the University of Minnesota with a $1.5 million donation to offer graduate programs at the Mayo Clinic in Rochester. During the same time period, the Mayo brothers created the Mayo Properties Association which converted the Mayo Clinic into a non-profit association practice. Mayo Properties Association later became the Mayo Foundation. These steps led to the university and Mayo Clinic to enter into an affiliation and teaching agreement. The curriculum during this period focused on the development of medical specialists during a time when the medical field was becoming further professionalized.
== Location ==
The Mayo Clinic College of Medicine …
