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The Ohio Christian athletic teams are called the Trailblazers. The university is a member of the National Christian College Athletic Association (NCCAA), competing as an independent in the Mideast Region at the Division I level. The Trailblazers previously competed in the River States Conference (RSC; formerly known as the Kentucky Intercollegiate Athletic Conference (KIAC) until after spring 2016) of the National Association of Intercollegiate Athletics (NAIA) from 2015–16 to 2023–24.
OCU competes in 19 intercollegiate varsity teams: Men's sports include baseball, basketball, cross country, golf, soccer, and track & field (indoor and outdoor); while women's sports include basketball, cross country, golf, soccer, softball, track & field (indoor and outdoor) and volleyball; and co-ed sports include disc golf and eSports. OCU plans to add women's swimming for the 2025/2026 academic year.
== Notable alumni ==
Jaron Crane, member of the Idaho House of Representatives
John C. Maxwell, author and leadership coach
Stan …