instruction.
=== Early twenty-first century ===
The Jay S. Sidhu School of Business & Leadership was created in 2004 and the university purchased a 80,000 sq ft (7,400 m2) building in downtown Wilkes-Barre. to house the expanding school. Initially named the Center on Main, the building houses the Sidhu School of Business and Leadership, an indoor track and field, and ropes course. In 2021 the Center on Main was formally named after Ron and Rhea Simms to be known as Simms Center on Main.
The Henry Student Center was expanded in 2005.
By 2014, Wilkes University grew to include eight academic buildings, 20 residence halls, nine administrative buildings, and other facilities such as the Eugene S. Farley Library, the Henry Student Center, and athletic complexes.
On April 17, 2015, Wilkes University dedicated the main university mailroom facility located on the second floor of the Henry Student Center as the Edward Elgonitis Sr. Mailroom or simply "Eddie's Mailroom" in honor of the thirty-three year dedicated Wilkes …