Texas was commissioned to design the college's Main Building. The structure was built four stories tall in the Gothic Revival style and was constructed with local white limestone.
=== Twentieth century ===
In 1903, a fire destroyed the majority of Main Building, but it was rebuilt by the fall. In 1922, Main Building sustained damage from a tornado that caused significant damage all over the campus. Main Building was added to the National Register of Historic Places in 1973. In 1925, St. Edward's received its university charter. Most of the personnel at the time were Holy Cross priests and brothers. Women arrived at St. Edward's in 1966 as students for Maryhill College, a coordinate institution. By 1970, Maryhill was absorbed and St. Edward's became co-educational.
By 1971, the university granted bachelor's and master's degrees in business administration. Also added were the College Assistance Migrant Program, or CAMP (1972); a professionally oriented Theater Arts curriculum (1972); a degree program for adults …