replaced in 1906 by Academic Hall, the school's domed landmark building. Academic Hall was designed by Jerome Bibb Legg, who also designed the St. Louis Exposition and Music Hall, and it includes light fixtures from the 1904 World's Fair. Academic Hall today stands at the center of campus and houses administrative offices, classrooms, and an auditorium.
In the 1950s, Southeast Missouri State College had an enrollment of approximately 1,600 students. Enrollment steadily increased to more than 7,000 students in the 1970s. The college moved away from its focus on training teachers and began to offer courses of study in business, nursing, and the liberal arts. The size campus grew rapidly in this same period. In 1956, the institution had ten buildings on campus. By 1975, the number had increased to twenty-two buildings.
In 1998, the university acquired the former St. Vincent's Seminary located in downtown Cape Girardeau on the Mississippi River. This property has been redeveloped as the River Campus, which opened …