The ERTC is located on the north side of the campus along New Poag Road and features lab and classroom space, as well as a 30,000 gallon-per-day wastewater treatment and drinking water treatment plant.
The university developed a 35-acre (14.2 ha) botanical garden, known as The Gardens at SIUE, that is also a living laboratory in support of the educational and research missions of the university. The Gardens are located off Cougar Lake Road, near the Cougar Lake Recreation Area and the Cougar Village apartments.
The Southwest Illinois Advanced Manufacturing Center (SIAM) was launched in 2005, performing applied and basic research for product/process development and improvement. The center was funded by the U. S. Department of Commerce Economic Development Administration. The Hoffman Center on the N.O. Nelson Campus of Lewis and Clark Community College in Edwardsville provided over 35,000 sq ft (3,300 m2) of space for SIAM. The center was closed in 2012.
=== Alton Campus ===
SIUE's campus in Alton, Illinois, …