Roanoke student Casey Smith won an individual national championship in the Division III women's 10,000m track and field event. In 2009, student Robin Yerkes secured Roanoke's fourth national championship when she won an individual championship in the Division III women's 400m track and field event. Yerkes is the most decorated athlete ever to graduate from Roanoke, earning 12 All-American honors in multiple events. In 2025, Mark Samuel won the NCAA Division III Wrestling Championship.
Conference championships
Roanoke teams have won 101 conference championships as of May 2013 (47 in men's sports, 54 in women's sports) since the college joined the ODAC as a founding member in 1976. Roanoke has won more conference championships than any other ODAC school in men's lacrosse with 18 titles and women's basketball with 13 titles. Roanoke, Hampden–Sydney College, and Randolph-Macon College are tied for the most conference championships in men's basketball with 10 titles each.
== Notable alumni ==
== Roanoke and …
