Douglass gave the commencement speech in 1854.
In 1838, the Loomis Observatory was built by astronomer Elias Loomis, and today remains the second oldest observatory in the United States, and the oldest still in its original location.
In 1852, the Medical School became the second medical school in the United States to graduate a woman, Nancy Talbot Clark. Five more women graduated over the next four years, including Emily Blackwell and Marie Zakrzewska, giving Western Reserve the distinction of graduating six of the first eight female physicians in the United States.
By 1875, Cleveland had emerged as the dominant population and business center of the region, and the city wanted a prominent higher education institution. In 1882, with funding from Amasa Stone, Western Reserve College moved to Cleveland and changed its name to Adelbert College of Western Reserve University. Adelbert was the name of Stone's son.
=== Case School of Applied Science (1880–1947) and Institute of Technology (1947–1967) ===
In 1877, …
